Finding a place for aliskiren in the wide spectrum of blood pressure lowering agents
نویسندگان
چکیده
منابع مشابه
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15 صفحه اولSustained blood pressure-lowering effect of aliskiren compared with telmisartan after a single missed dose.
Poor adherence to antihypertensive drug treatment is common and is often associated with marked prolongations of the dosing interval. Hence, selecting a treatment that has the potential to provide a sustained blood pressure (BP)-lowering effect is important. The objective of this analysis is to compare the sustained efficacy of aliskiren with telmisartan after a single missed dose. This is part...
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Blood pressure lowering in essential hypertension with an oral renin inhibitor, aliskiren.
Inhibition of the first and rate-limiting step of the renin-angiotensin system has long been an elusive therapeutic goal. Aliskiren, the first known representative of a new class of completely nonpeptide, orally active, renin inhibitors, has been shown to inhibit the production of angiotensin I and II in healthy volunteers and to reduce blood pressure (BP) in sodium-depleted marmosets. The aim ...
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ژورنال
عنوان ژورنال: Hypertension Research
سال: 2011
ISSN: 0916-9636,1348-4214
DOI: 10.1038/hr.2011.159