منابع مشابه
Fighting fat
A growing epidemic is sweeping through the developed world, threatening millions with disability and death: obesity. ‘Epidemic’ may sound exaggerated, but the facts speak for themselves: 154 million people worldwide are obese—or more than 20% are over their ideal body weight—including more than 50% of all Americans. More disturbing is the prevalence of childhood obesity, which has jumped dramat...
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In this issue of Blood, Dany et al demonstrate a critical role of the ceramideregulated signaling pathway in inducing mitophagy to cause cell death and overcome drug resistance of acute myeloid leukemia (AML) cells carrying internal tandem duplication (ITD) of the Fms-like tyrosine kinase 3 (FLT3) gene. Inhibition of FLT3-ITD signaling through altering ceramide-involved lipid metabolism provide...
متن کاملHealing hearts and fighting fat
T cell receptors (TCRs) band together to detect minute amounts of antigen, according to Schamel and colleagues on page 493. Their new work shows that TCRs are expressed on the surface of resting T cells either individually or in groups. The grouped TCRs, but not the solitary receptors, were triggered by low dose antigen, suggesting that these receptors must cooperate when antigen is scarce. Whe...
متن کاملColeus forskohlii: Fat-Fighting and More
Coleus forskohlii, is a member of the mint family (Lamiaceae). As part of a long-standing tradition in India, C. forskohlii roots have been used as a marinated food, or pickle, that is commonly eaten as part of a vegetarian meal. Upon closer investigation into the plant's pharmacological properties, it was revealed that C. forskohlii roots contain forskolin, a compound that belongs to the chemi...
متن کاملMass education for obesity prevention: the penetration of the BBC's 'Fighting Fat, Fighting Fit' campaign.
The study aimed to evaluate the BBC's 'Fighting Fat, Fighting Fit' campaign's success in achieving public awareness of the need for obesity prevention, and putting over its message of healthy eating and increased physical activity. Demographic factors associated with awareness of the campaign were assessed. Data were collected from a national representative British sample as part of the ONS Omn...
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ژورنال
عنوان ژورنال: EMBO reports
سال: 2002
ISSN: 1469-221X,1469-3178
DOI: 10.1093/embo-reports/kvf148