Fibrosis: Altered gene expression in TGF-β stimulated human fibroblasts of the Tenon
نویسندگان
چکیده
منابع مشابه
Extracellular matrix elasticity modulates TGF-β-induced p38 activation and myofibroblast transdifferentiation in human tenon fibroblasts.
PURPOSE Extracellular matrix and the cytokine TGF-β influence scar formation in an interdependent fashion. In this study, the impact of extracellular matrix elasticity on TGF-β-induced signal transduction and myofibroblast transdifferentiation was examined. METHODS Primary human tenon fibroblasts were seeded on collagen-coated glass coverslips (rigid environment) or collagen or polyacrylamide...
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ژورنال
عنوان ژورنال: Current Directions in Biomedical Engineering
سال: 2020
ISSN: 2364-5504
DOI: 10.1515/cdbme-2020-3111