Fibrinogen and Its Degradation Products as Thrombotic Risk Factors
نویسندگان
چکیده
منابع مشابه
Fibrinogen-fibrin degradation products.
The identification of the molecular structure of fibrinogen has given a better understanding of many clinical conditions associated with abnormalities of fibrinogen. Proteolysis of fibrinogen or fibrin by its natural lytic enzyme, plasmin, leads to the formation of degradation products which are of great importance in the laboratory diagnosis of many pathological conditions. The biochemical and...
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The isolation and characterization of carp (Cyprinus carpio) plasma fibrinogen and its plasmin degradation products are described. Alike other vertebrate species, carp fibrinogen is a dimeric protein and consists of three different pairs of disulfide-bonded polypeptide chains. Aa, B/f, and y. In contrast to mammalian fibrinogen, the B0 chain of carp fibrinogen has apparently a higher molecular ...
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An increase in low molecular weight fibrin-fibrinogen degradation products (FDP) was demonstrated in cerebrospinal fluid (CSF) from 17 of 18 patients with bacterial or viral meningitis compared with 29 patients without meningitis. The CSF also showed an increase in coagulation proteins of molecular weight less than 90000 (factors VII, IX, and plasminogen) but did not contain fibrinogen (MW 3400...
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The serum and urine concentrations of fibrin/fibrinogen degradation products (F.D.P.) were estimated in 172 patients with glomerulonephritis. In each case the diagnosis was established on the basis of clinical, renal histological, and ultrastructural findings. Serum F.D.P. concentrations were often raised in all types of glomerulonephritis, though more consistently in active proliferative forms...
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There are four hypotheses which have been advanced to explain the pathophysiology of severe and complicated malaria such as cerebral malaria. However, none of them adequately explains all the features of cerebral malaria in man. One such hypotheses is Disseminated Intravascular Coagulation (DIC). To determine whether this condition occurs in patients with uncomplicated malaria, the authors cond...
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ژورنال
عنوان ژورنال: Annals of the New York Academy of Sciences
سال: 2006
ISSN: 0077-8923,1749-6632
DOI: 10.1111/j.1749-6632.2001.tb03544.x