Fiber-chimeric adenoviruses expressing fibers from serotype 16 and 50 improve gene transfer to human pancreatic adenocarcinoma
نویسندگان
چکیده
منابع مشابه
Serotype Chimeric Human Adenoviruses for Cancer Gene Therapy
Cancer gene therapy consists of numerous approaches where the common denominator is utilization of vectors for achieving therapeutic effect. A particularly potent embodiment of the approach is virotherapy, in which the replication potential of an oncolytic virus is directed towards tumor cells to cause lysis, while normal cells are spared. Importantly, the therapeutic effect of the initial vira...
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ژورنال
عنوان ژورنال: Cancer Gene Therapy
سال: 2009
ISSN: 0929-1903,1476-5500
DOI: 10.1038/cgt.2009.4