Fetal Myelomeningocele Repair through a Mini-Hysterotomy

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Fetal Myelomeningocele Repair through a Mini-Hysterotomy.

OBJECTIVE To present the feasibility of fetal myelomeningocele (MMC) repair through a mini-hysterotomy and to describe the perinatal results from our initial experience. METHODS A descriptive study of cases of fetal MMC correction via mini-hysterotomy performed between 2014 and 2016. RESULTS Forty-five women underwent fetal surgery and 87% (39/45) delivered. A complete multilayer correction...

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Fetal myelomeningocele repair: a new standard of care.

Myelomeningocele, also known as spina bifida, is one of the most common congenital anomalies of the central nervous system and the most common open, prenatally repaired birth defect. The Management of Myelomeningocele Study (MOMS), which compared the results of prenatal and postnatal myelomeningocele repair, found prenatal surgery to be much more effective than postnatal surgery. During surgery...

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Tissue engineering strategies for fetal myelomeningocele repair in animal models.

Myelomeningocele (MMC), the most severe form of spina bifida, is a common and devastating malformation. Over two decades of experimental work in animal models have led to the development and clinical application of open fetal surgery for the repair of the MMC defect. This approach offers improved neurofunctional outcomes and is now a clinical option for the management of prenatally diagnosed MM...

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Fetal surgery for myelomeningocele?

The possibility of surgical repair of fetal anomalies in utero has long tantalized obstetricians and pediatric surgeons, especially since the development of high-resolution real-time ultrasonography. The presumption has been that earlier in utero repair would provide superior outcomes for the offspring than would postnatal surgery. However, postnatal treatment is much simpler and is not traumat...

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ژورنال

عنوان ژورنال: Fetal Diagnosis and Therapy

سال: 2016

ISSN: 1015-3837,1421-9964

DOI: 10.1159/000449382