Ferulol and epi-Samarcandin, Two New Sesquiterpene Coumarins from Ferula Sinaica

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Two New Sesquiterpene Coumarins, Ferusinol and Samarcandin Diastereomer, from Ferula sinaica

Re-investigation of the methylene chloride extract of the roots of Ferula sinaica gave ferusinol, a new sesquiterpene coumarin with a rare carbon skeleton, and samarcandin diastereomer. The structures elucidation were determined by MS, 1H- 13C-1D and 2D NMR spectral data.

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Two New Sesquiterpene Coumarins, Ferusinol and Samarcandin Diastereomer, from Ferula sinaica

Re-investigation of the methylene chloride extract of the roots of Ferula sinaica gave ferusinol, a new sesquiterpene coumarin with a rare carbon skeleton, and samarcandin diastereomer. The structures elucidation were determined by MS, 1H- 13C-1D and 2D NMR spectral data.

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two new sesquiterpene coumarins, ferusinol and samarcandin diastereomer, from ferula sinaica

re-investigation of the methylene chloride extract of the roots of ferula sinaica gave ferusinol, a new sesquiterpene coumarin with a rare carbon skeleton, and samarcandin diastereomer. the structures elucidation were determined by ms, 1h- 13c-1d and 2d nmr spectral data.

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Sesquiterpene Coumarins from Ferula sinkiangensis Act as Neuroinflammation Inhibitors.

Neuroinflammation mediated by microglia cells plays a critical role in the development of Alzheimer's disease. To identify novel natural neuroinflammation inhibitors, a bioactivity-guided phytochemical research was performed on the traditional Chinese medicine "Awei", that exhibited a significant inhibitory effect on nitric oxide production in over-activated microglia cells. The research identi...

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ژورنال

عنوان ژورنال: Natural Product Communications

سال: 2007

ISSN: 1934-578X,1555-9475

DOI: 10.1177/1934578x0700200502