Fenofibrate: direct attenuating effects on tumor growth
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چکیده
منابع مشابه
Fenofibrate: direct attenuating effects on tumor growth
The recent article by Liu et al. [1] provided for highly stimulating and interesting reading. Interestingly, recent data suggests that fenofibrate may directly attenuate tumor growth in a number of systemic malignancies. For instance, fenofibrate is of benefit in mitigating tumor progression in prostatic malignancies. It has a negative impact on intercellular coupling via gap junctions between ...
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Angiogenesis and inflammation are central processes through which the tumor microenvironment influences tumor growth. We have demonstrated recently that peroxisome proliferator-activated receptor (PPAR)alpha deficiency in the host leads to overt inflammation that suppresses angiogenesis via excess production of thrombospondin (TSP)-1 and prevents tumor growth. Hence, we speculated that pharmaco...
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Background. To evaluate the effect of rosiglitazone, fenofibrate, or their combined use on plasma lipids in normoglycemic healthy adults. Methods and Results. Subjects were randomized in a double-blind fashion to rosiglitazone + placebo, fenofibrate + placebo, rosiglitazone + fenofibrate, or matching double placebo. The between-group difference in the change in fasting TG, high-density lipoprot...
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In humans, clofibrate increases the degree of bile cholesterol saturation and predisposes patients to cholesterol gallstone formation. To determine if this activity extends to the related hypolipidemic agent fenofibrate, duodenal bile lipid composition was studied in 15 subjects before they participated in a double-blind study of that drug. Eight subjects were studied again on fenofibrate and s...
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1.0 overview it seems that grammar plays a crucial role in the area of second and foreign language learning and widely has been acknowledged in grammar research. in other words, teaching grammar is an issue which has attracted much attention to itself, and a lot of teachers argue about the existence of grammar in language teaching and learning. this issue will remind us a famous sentence f...
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ژورنال
عنوان ژورنال: Radiation Oncology Journal
سال: 2013
ISSN: 2234-1900,2234-3156
DOI: 10.3857/roj.2013.31.1.55