منابع مشابه
Feedback System Protects Inner Ear
Rock 'n' roll sounds best turned up loud, but as hundreds of aging rockers (and millions of their aging fans) are discovering, the cost of all that glorious noise is hearing loss and tinnitus. And it's not just loud music—our ears are daily assaulted by the roar of the jet engine, the shriek of the power tool, the blare of the car horn, and the pounding of the jackhammer. In most cases, it seem...
متن کاملAutoimmune Inner Ear Disease- A Clinical Viewpoint
Recent developments in medicine have given us a better insight into a group of disorders known as autoimmune diseases. In particular, advances have occurred in our understanding of the Autoimmune Inner Ear Disease (AIED). In this article, the authors review the different postulated theories in the pathogenesis of this disease. The clinical presentation, the available para-clinical diagnostic to...
متن کاملInside the inner ear
There are dozens of different myosin isozymes, though it's not clear why cells require such a diversity. These images of fluorescently-labelled hair cells from the inner ears of frog, guinea pig and mouse show the localization of actin (red at top left and bottom right) and of four different forms of myosin (green, except at bottom left, where myosin VI is labelled in red). Hair cells are the r...
متن کاملBiomechanics in the Inner Ear
The elongation and contraction of outer hair cells (OHCs) greatly contribute to the high sensitivity and frequency selectivity of the mammalian inner ear. The motility of OHCs is believed to be based on the conformational changes of the motor protein prestin in the plasma membrane of OHCs. In the present study, four lines of research on the inner ear were conducted. First, the mechanism by whic...
متن کاملLeupeptin, a calpain inhibitor, protects inner ear hair cells from aminoglycoside ototoxicity.
Inner ear hair cells play a major role in the auditory pathway that converts sound stimulation into electrical signals, and then into a neural code. However this function is often lost by aminoglycoside ototoxicity. The injury of inner ear hair cells from aminoglycoside treatment is considered apoptosis, and caspase is an important participant in the apoptosis pathway in many organs. It has bee...
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ژورنال
عنوان ژورنال: PLoS Biology
سال: 2009
ISSN: 1545-7885
DOI: 10.1371/journal.pbio.1000012