FEATURES OF THE EXCIPIENTS SELECTION FOR SEMI-SOLID DOSAGE FORMS
نویسندگان
چکیده
منابع مشابه
New pharmaceutical excipients in solid dosage forms – A review
The objective of a medicinal formulation development project is to deliver drug to the patient in the required amount, at the required rate, consistently within a batch, from batch to batch, and over the product’s shelf life. To produce a drug substance in a final dosage form requires pharmaceutical ingredients. In selecting excipients for pharmaceutical; dosage forms and drug products the deve...
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FELICIA DRAGAN1, IRINA KACSO2, FLAVIA MARTIN2*, GHEORGHE BORODI2, IOAN BRATU2, MARCEL COSTULEANU3, IOAN GABRIEL SANDU4,5*, VLADIMIR POROCH6,7 1 Oradea University, Faculty of Medicine and Pharmacy, 1 Armatei Romane Str., 410087, Oradea, Romania 2 National Institute for Research and Development of Isotopic and Molecular Technologies, 67-103 Donat Str., 400293, Cluj Napoca, Romania, 3 Grigore T. P...
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The tablets manufactured by direct compression method using co-processed excipient showed relatively better disintegration time and in vitro drug release, with omission of number of laborious steps as compared to tablets manufactured by conventional wet granulation method. Melt granulation technique is a potential alternative for the development of directly compressible adjuvants. Lactose and m...
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The delivery of phages to epithelial surfaces for therapeutic outcomes is a realistic proposal, and indeed one which is being currently tested in clinical trials. This paper reviews some of the known research on formulation of phages into semi-solid dosage forms such as creams, ointments and pastes, as well as solid dosage forms such as troches (or lozenges and pastilles) and suppositories/pess...
متن کاملCharacterization and Evaluation of Spray Dried Co- Processed Excipients and Their Application in Solid Dosage Forms
Major challenge for tablet manufacture comes from the powder characteristics of the materials to be compressed. This in turn poses a challenge in achieving greater productivity and better quality product especially on the new generation high-speed machines. Advancement in directly compressible materials has come in the form of co processed spray dried materials. The present work evaluates and ...
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ژورنال
عنوان ژورنال: Фармацевтичний часопис
سال: 2015
ISSN: 2312-0967
DOI: 10.11603/2312-0967.2015.1.3759