Feasibility of Utilizing Transforming Growth Factor Beta as a Biomarker of Depression in Hospitalized Patients

Several mental conditions and depression, have been linked to immune response disorganization. However, it is unclear if particular mediators play a part in the etiopathogenesis of depression. Although there are no definite biomarkers diagnose current study sought logically evaluate possibility feasibility checking biomarker for depression be utilized hospitalized patients suspected In this narrative review, related articles were gathered through search PubMed, Scopus, ScienceDirect databases as well manual full-text paper references. The reviewed studies demonstrated potential role transforming growth factor beta (TGF-β) depressive disorders. Previous represented negative TGF-β pathophysiology an increase after treatment. Elevated plasma TGF-alpha acted controversial TGF-β. level maternal increased getting close delivery, researchers found that might associated with postpartum addition, reported extreme elevations levels brain cells subjects who died by suicide. results revealed plausible link between based on literature, sensitivity specificity needed before may extensively employed clinical practice. Depression appears down-regulating its signaling or underlying mechanisms pathogenesis consequent neurological disorders, while further required application assessment