Fe2+ substrate transport through ferritin protein cage ion channels influences enzyme activity and biomineralization
نویسندگان
چکیده
منابع مشابه
Ion transport through biological channels
The transport of ions across single-molecule protein nanochannels is important both in the biological context and in proposed nanotechnological applications. Here we discuss these systems from the perspective of non-equilibrium physics, and in particular, whether the concepts underlying the physics of diffusive and electrokinetic transport can be employed to predict and understand these systems...
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We discuss various models of ion transport through cell membrane channels. Recent experimental data shows that sizes of ion channels are compared to those of ions and that only few ions may be simultaneously in any single channel. Theoretical description of ion transport in such channels should therefore take into account interactions between ions and between ions and channel proteins. This is ...
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ABSRACT Nanoparticle arrays biologically derived from an electrochemicallycontrolled site-specific biomineralization were fabricated on a gold substrate through the immobilization process of biomolecules. The work reported herein includes the immobilization of ferritin with various surface modifications, the electrochemical biomineralization of ferritins with different inorganic cores, the fabr...
متن کاملStochastic Modeling and Simulation of Ion Transport through Channels
Abstract Ion channels are of major interest and form an area of intensive research in the fields of biophysics and medicine, since they control many vital physiological functions. The aim of this work is to propose a fully stochastic model describing the main characteristics of a multiple channel system, in which ion movement is coupled with a Poisson–Nernst–Planck equation. Exclusion forces ar...
متن کاملSimulation study of the transport properties of ions through ion channels serving as primary components of a nanobiosensor
Ion channels are naturally occurring pores through the proteins that regulate the passage of ions and thus maintain the concentration of ions inside and outside the cell. The ion channels control many physiological functions and they can show selectivity for a specific ion. Ion channels are mostly observed in nerve cells and muscle cells. The influx of ions into cells can be regulated by a gate...
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ژورنال
عنوان ژورنال: JBIC Journal of Biological Inorganic Chemistry
سال: 2015
ISSN: 0949-8257,1432-1327
DOI: 10.1007/s00775-015-1279-x