Fatty acid biosynthesis and transcriptional regulation of Stearoyl-CoA Desaturase 1 (SCD1) in buffalo milk

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Investigation of (Stearoyl-CoA Desaturase 1) SCD1 Gene Polymorphism in Khuzestan Buffalo Population Using PCR-RFLPMethod

Stearoyl-CoA desaturase (SCD) is a rate-limiting enzyme in the biosynthesis of monounsaturated fatty acids (MUFA). A number of studies support the hypothesis that SCD gene regulation and polymorphism may affect fatty acid composition and fat quality in meat and milk. Single nucleotide polymorphisms in the coding region of the bovine stearoyl-CoA desaturase gene have been predicted to result in ...

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investigation of (stearoyl-coa desaturase 1) scd1 gene polymorphism in khuzestan buffalo population using pcr-rflpmethod

stearoyl-coa desaturase (scd) is a rate-limiting enzyme in the biosynthesis of monounsaturated fatty acids (mufa). a number of studies support the hypothesis that scd gene regulation and polymorphism may affect fatty acid composition and fat quality in meat and milk. single nucleotide polymorphisms in the coding region of the bovine stearoyl-coa desaturase gene have been predicted to result in ...

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An Evolutionary Relationship Between Stearoyl-CoA Desaturase (SCD) Protein Sequences Involved in Fatty Acid Metabolism

Background: Stearoyl-CoA desaturase (SCD) is a key enzyme that converts saturated fatty acids (SFAs) to monounsaturated fatty acids (MUFAs) in fat biosynthesis. Despite being crucial for interpreting SCDs’ roles across species, the evolutionary relationship of SCD proteins across species has yet to be elucidated. This study aims to present this evolutionary relationship based on amino aci...

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Mismatch between the uptake and utilization of long-chain fatty acids in the myocardium leads to abnormally high intracellular fatty acid concentration, which ultimately induces myocardial dysfunction. Stearoyl-Coenzyme A desaturase-1 (SCD1) is a rate-limiting enzyme that converts saturated fatty acids (SFAs) to monounsaturated fatty acids. Previous studies have shown that SCD1-deficinent mice ...

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Expression and Nutritional Regulation of Stearoyl-CoA Desaturase Genes in the Ruminant Mammary Gland: Relationship with Milk Fatty Acid Composition

In lactating ruminants, stearoyl-CoA desaturase ( SCD ) gene expression in the mammary gland focused particular attention due to its implication in milk technological and nutritional qualities for human consumers. Indeed, the mammary enzyme SCD or ∆9-desaturase by introducing a cis double bond between carbons 9 and 10 of the fatty acids (FA) has a key role in the synthesis of milk monounsaturat...

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ژورنال

عنوان ژورنال: BMC Genetics

سال: 2020

ISSN: 1471-2156

DOI: 10.1186/s12863-020-0829-6