Fatty acid binding protein 3 is associated with peripheral arterial disease
نویسندگان
چکیده
منابع مشابه
Periaortic Fat Deposition Is Associated With Peripheral Arterial Disease
Background—Central obesity is associated with peripheral arterial disease, suggesting that ectopic fat depots may be associated with localized diseases of the aorta and lower-extremity arteries. We hypothesized that persons with greater amounts of periaortic fat are more likely to have clinical PAD and a low ankle-brachial index. Methods and Results—We quantified periaortic fat surrounding the ...
متن کاملSerum fatty acid-binding protein 4 (FABP4) concentration is associated with insulin resistance in peripheral tissues, A clinical study
Type 2 diabetes mellitus (T2DM) is caused by insulin resistance and β cell dysfunction. In recent studies reported that several markers associated with insulin sensitivity in skeletal muscle, Adiponectin and other parameters, such as fatty acid-binding protein (FABP4), have been reported to regulate insulin resistance, but it remains unclear which factor mostly affects insulin resistance in T2D...
متن کاملHuman intestinal fatty acid binding protein 2 expression is associated with fat intake and polymorphisms.
The intestinal fatty acid binding protein (FABP2) is involved in lipid metabolism whereby variations in the promoter (haplotypes A/B) and exon 2 (Ala54Thr) are associated with dyslipidemia and insulin resistance. To elucidate which factors determine FABP2 expression in human mucosa, we investigated the association between fat intake, genotypes, biochemical variables, and FABP2 expression. FABP2...
متن کاملHeart-Type Fatty Acid Binding Protein Is Associated with Proteinuria in Obesity
RATIONALE Lipid metabolism contributes to the formation of obesity-related glomerulopathy (ORG). Heart-type fatty acid binding protein (H-FABP or FABP3) is involved in lipid metabolism and was predicted to relate to renal lesions in obesity. METHODS A total of 28 patients with ORG were investigated, and renal tissue from 7 kidney donors served as controls. Db/db mice with albuminuria were tre...
متن کاملAdipocyte fatty acid-binding protein is a plasma biomarker closely associated with obesity and metabolic syndrome.
BACKGROUND Adipocyte fatty acid-binding protein (A-FABP) is traditionally thought to be a cytosolic fatty acid chaperone expressed in adipocytes. Mice with targeted disruption of the A-FABP gene exhibit a striking phenotype with strong protection from insulin resistance, hyperglycemia, and atherosclerosis. The clinical relevance of these findings remains to be confirmed. METHODS We used tande...
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ژورنال
عنوان ژورنال: JVS: Vascular Science
سال: 2020
ISSN: 2666-3503
DOI: 10.1016/j.jvssci.2020.08.003