Family Physician Perspectives on Primary Immunodeficiency Diseases

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Family Physician Perspectives on Primary Immunodeficiency Diseases

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Current Perspectives on Primary Immunodeficiency Diseases

Since the original description of X-linked agammaglobulinemia in 1952, the number of independent primary immunodeficiency diseases (PIDs) has expanded to more than 100 entities. By definition, a PID is a genetically determined disorder resulting in enhanced susceptibility to infectious disease. Despite the heritable nature of these diseases, some PIDs are clinically manifested only after prereq...

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Primary immunodeficiencies (PID) are genetic disorders of immunity whose incidence varies from 1:250 to 1:1,000,000 depending of disease and study population. Because of incomplete records of immunodeficiency in the world, is estimated that the prevalence of 1:5,000 to 1:100,000 (Geha et al., 2007; Boyle & Buckley, 2007; Notarangelo,et al., 2010). Thus, the PID is a important group to public he...

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ژورنال

عنوان ژورنال: Frontiers in Medicine

سال: 2016

ISSN: 2296-858X

DOI: 10.3389/fmed.2016.00012