Familial breast cancer in a normal population

RAD51B in Familial Breast Cancer.

Common variation on 14q24.1, close to RAD51B, has been associated with breast cancer: rs999737 and rs2588809 with the risk of female breast cancer and rs1314913 with the risk of male breast cancer. The aim of this study was to investigate the role of RAD51B variants in breast cancer predisposition, particularly in the context of familial breast cancer in Finland. We sequenced the coding region ...

[Familial breast cancer].

Japanese breast cancer families were collected and classified into the following 7 types according to the onset age and the distribution of other cancers in the family lines; early-onset type, late-onset type, familial breast-ovarian cancer type, familial breast-prostate cancer type, familial breast-thyroid cancer type, familial male and female breast cancer type and multiple primary cancer typ...

APOBEC3 Deletion is Associated with Breast Cancer Risk in a Sample of Southeast Iranian Population

Breast Cancer (BC) is considered as one of the most important causes of death worldwide. Previous studies showed that apolipoprotein B mRNA- editing catalytic polypeptide-like 3 (APOBEC3) gene deletion significantly increased the risk of BC risk in Chinese and European women. The present study aimed to assess the possible impact of APOBEC3 deletion and the risk of BC in a sample of Iranian popu...

prevalence of breast cancer in a defined population of iran

Familial Breast and Ovarian Cancer

This text book is a timely publication and it gives a splendid overview of the genetics and management of familial breast and ovarian cancer. The book is edited by Professor Morrison and his colleagues and they have drawn together a national and an international list ofcontributors well respected in their fields. The book begins with a series of book chapters on molecular biology of these tumours.