Factors affecting authentic 5' splice site selection in plant nuclei.
نویسندگان
چکیده
منابع مشابه
Intronic and exonic sequences modulate 5' splice site selection in plant nuclei.
Pre-mRNA transcripts in a variety of organisms, including plants, Drosophila and Caenorhabditis elegans, contain introns which are significantly richer in adenosine and uridine residues than their flanking exons. Previous analyses using exonic and intronic replacements between two nonequivalent 5'splice sites in the 469 nt long rbcS3A intron 1 provided the first evidence indicating that, in bot...
متن کاملAlternative pre-mRNA splicing: factors involved in splice site selection.
The protein-coding regions of most vertebrate genes are split, giving rise to primary transcripts containing introns and exons; the latter must be spliced in the nucleus to form the mature mRNA, which then moves to the cytoplasm for translation. Pre-mRNA splicing, the process of intron removal and exon joining, represents an important function within the nucleus, and elucidation of the mechanis...
متن کاملFactors affecting heavy metal uptake in plant selection for phytoremediation.
The heavy metal uptake of ten plant species was studied under different soil and climatic conditions. Effects of soil pH, temperature, plant species and phenophase on the heavy metal content of stems and leaves were determined in pot experiments. Plants and soil samples were collected from a lead/zinc mine ore (Gyöngyösoroszi, Hungary) and characterised by high contents of Pb, Zn, As, Cd, Cu. T...
متن کاملIntrinsic differences between authentic and cryptic 5' splice sites.
Cryptic splice sites are used only when use of a natural splice site is disrupted by mutation. To determine the features that distinguish authentic from cryptic 5' splice sites (5'ss), we systematically analyzed a set of 76 cryptic 5'ss derived from 46 human genes. These cryptic 5'ss have a similar frequency distribution in exons and introns, and are usually located close to the authentic 5'ss....
متن کاملSplice site selection in the dystrophin gene
The dystrophin gene is the largest gene in the human genome, and it codes for a protein which plays an important role in anchoring the cytoskeleton to the cell membrane. Mutations in the gene may cause Duchenne muscular dystrophy (DMD) or Becker muscular dystrophy (BMD), an allelic variant. Currently genetic therapy holds great promise in finding a cure through exon skipping by restoring the pr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 1993
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.13.3.1323