Factor VIII related antigen in the assessment of vasculitis.
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چکیده
منابع مشابه
Factor VIII related antigen in the assessment of vasculitis.
Factor VIII related antigen, an endothelial cell product, was markedly raised in systemic necrotising arteritis, reflecting disease activity, but was not raised in active cutaneous vasculitis. In rheumatoid arthritis high levels were only found in systemic vasculitis or Felty's syndrome, but in other connective tissue diseases increased levels were more frequently detected and usually related t...
متن کاملImmunohistochemical localisation of factor VIII-related antigen in Hodgkin's disease.
A series of 45 lymph nodes involved by Hodgkin's disease have been examined by means of the unlabelled antibody peroxidase-antiperoxidase (PAP) method for the demonstration of factor VIII-related antigen (F VIII R Ag). In addition, five lymph nodes showing reactive follicular hyperplasia were studied. In the specimens of nodular sclerosing Hodgkin's disease, many blood vessels were present, as ...
متن کاملLocalization of factor-VIII-related antigen in human vascular subendothelium.
Factor-VIII-related antigen has previously been shown to be synthesized by vascular endothelial cells. Using both an immunofluorescent staining technique and electron microscopy, we have demonstrated the presence of factor-VIII-related antigen in human vascular subendothelium. This finding may have implications in the mechanism of platelet adhesion to deendothelialized blood vessel surfaces.
متن کاملFactor-VIII-related antigen: multiple molecular forms in human plasma.
Analysis of Factor-VIII-related antigen (vWAg) in normal plasma by crossed immunoelectrophoresis reveals an asymmetric pattern indicative of molecular heterogeneity. This asymmetric pattern apparently results from the presence of multiple molecular forms of VWAg with distinct, though partially overlapping, mobilities on crossed immunoelectrophoresis. Evidence for this conclusion has been obtain...
متن کاملElectrophoretic studies of human factor VIII-related antigen [proceedings].
I I the inherent lytic rate of cross-linked and non-cross-linked clots. To investigate this, a fibrin-plate techique was used in which small equal volumes of haemoglobin solution were spotted on to the plates instead ofthestreptokinase solution,and therateof diffusion of the haemoglobin into the plates was estimated. Yet again this was unaffected by crosslinking, and, since streptokinase has an...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1987
ISSN: 0003-4967
DOI: 10.1136/ard.46.6.441