Factor-V Leiden: a risk factor for cerebral palsy

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Factor V Leiden Mutation Is a Risk Factor for Cerebral Venous Thrombosis

Background and Purpose—Different coagulation disorders have been associated with cerebral venous thrombosis (CVT). Until now, fewer than 50 patients have been reported with CVT and the factor V Leiden (FVL) mutation. Although the prevalence of FVL-positive patients with CVT ranged from 10% to 25%, it was as low as 0.5% to 3% in the control groups. Most other studies had not systematically searc...

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Thrombophilia: a risk factor for cerebral palsy?

BACKGROUND The cause of cerebral palsy remains unknown in most cases. Factor V Leiden mutation, a common cause of hereditary thrombophilia, has been associated with CP. OBJECTIVES To analyze the prevalence of factor V Leiden (G1691A), prothrombin (G20210A), and methylenetetrahydrofolate reductase (C677T) mutations in children with CP. METHODS Sixty-one Jewish and Arab children with CP were ...

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Factor V Leiden and perioperative risk.

Factor V Leiden (FVL) is the most common known inherited cause of thrombophilia; it is present in approximately 5% of the Caucasian population. Although the risk of venous thrombosis associated with this polymorphism in various medical settings is well described, its effect on perioperative risk is only beginning to be explored. Specifically, there are few studies addressing the potential risks...

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factor v leiden, factor v cambridge, factor ii ga20210 and mtfhr in cerebral venous and sinus thrombosis: a case-control study

background: factor v g1691a (fv leiden), fii ga20210, and methylenetetrahydrofolate reductase (mthfr) c677t mutations are the most common genetic risk factors for thromboembolism in the western countries. however, there is rare data in iran about cerebral venous and sinus thrombosis (cvst) patients. the aim of this study was to evaluate the frequency of common genetic thrombophilic factors in c...

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Factor V Leiden mutation is a risk factor for cerebral venous thrombosis: a case-control study of 55 patients.

BACKGROUND AND PURPOSE Different coagulation disorders have been associated with cerebral venous thrombosis (CVT). Until now, fewer than 50 patients have been reported with CVT and the factor V Leiden (FVL) mutation. Although the prevalence of FVL-positive patients with CVT ranged from 10% to 25%, it was as low as 0.5% to 3% in the control groups. Most other studies had not systematically searc...

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ژورنال

عنوان ژورنال: Developmental Medicine & Child Neurology

سال: 2007

ISSN: 0012-1622,1469-8749

DOI: 10.1111/j.1469-8749.1999.tb00539.x