Factor concentrates for treatment of hemophilia: which one to choose? [see comments]
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چکیده
منابع مشابه
Factor concentrates for treatment of hemophilia: which one to choose?
U NTIL THE ADVENT of components that could more specifically replace specific missing clotting factors, patients with hemophilia were treated with whole blood and then plasma. Such patients had a shortened lifespan and were crippled with severe anthropathy; many died of hemonrhage. With the discovery in 1960 that factor VIII:C was concentrated in cryoprecipitate, more specific replacement for p...
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In high-income countries, the large availability of coagulation factors for replacement therapy of patients with hemophilia A has raised the life expectancy of these lifelong bleeders to that of males from the general population. The practicing clinician is offered a multitude of choices among several commercial brands of factor VIII extracted from human plasma or engineered from mammalian cell...
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ژورنال
عنوان ژورنال: Blood
سال: 1989
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v73.8.2067.2067