Extubation Airway Emergency after Spinal Fusion Using Bone Morphogenetic Protein

Vertebral bone resorption after transforaminal lumbar interbody fusion with bone morphogenetic protein (rhBMP-2).

OBJECTIVE Bone morphogenetic protein (rhBMP-2) has demonstrated an increased rate of interbody fusion when placed in the intervertebral space. Owing to this advantage, rhBMP-2 is being implanted with increasing frequency in the lumbar spine. The purpose was to quantify and describe the presence of bone resorption within the vertebral body after transforaminal lumbar interbody fusion with placem...

Spinal Fusion With Bone Morphogenetic Protein-2 Delivered by hydroxyapatite/collagen in a Rabbit

Recombinant Human Bone Morphogenetic Protein-2 in Posterolateral Spinal Fusion: What's the Right Dose?

STUDY DESIGN Single center retrospective cohort analysis. PURPOSE The goal was to evaluate the influence of varying amount of recombinant human bone morphogenetic protein 2 (rhBMP-2) per level on fusion rates and complications in posterolateral spinal fusions. OVERVIEW OF LITERATURE rhBMP-2 has been utilized for lumbar posterolateral fusions for many years. Initial rhBMP-2 recommendations w...

1052 - Study on Carriers of Bone Morphogenetic Protein Used for Spinal Fusion

Introduction. Osteoinductive growth factors, such as bone morphogenetic proteins (BMPs), are known to stimulate osteoblast differentiation and synthetic activity. The soluble osteoinductive growth factor requires a less soluble carrier for expression of its biologic potency. We have reported the efficacy of the sintered bovine bone named True Bone Ceramics (TBC) coated with type I collagen as a...

Bone morphogenetic protein signalling in airway epithelial cells during regeneration.

Mechanisms of lung regeneration after injury remain poorly understood. Bone morphogenetic protein 4 (BMP4) is critical for lung morphogenesis and regulates differentiation of the airway epithelium during development, although its mechanism of action is unknown. The role of BMPs in adult lungs is unclear. We hypothesised that BMP signalling is involved in regeneration of damaged adult airways af...