Extraintestinal complications of inflammatory bowel diseases

نویسندگان

چکیده

Idiopatick?Š st??evn?­ z??nÄ?ty (IBD - inflammatory bowel disease) zahrnuj?­ Crohnovu chorobu (CN) a ulcer??zn?­ kolitidu (UC). Jedn?? se o chronick?? z??nÄ?tliv?? onemocnÄ?n?­ tr??vic?­ho traktu ne zcela zn??m?Š etiologie. Vzhledem k jejich imunitnÄ? mediovan?Šmu mechanismu komplexn?­mu p??soben?­ na cel?? organismus mohou b??t r??zn??m zp??sobem posti?ženy i jin?Š org??ny ne?ž jen gastrointestin??ln?­ trakt. Tyto extraintestin??ln?­ manifestace (EIM) komplikace z??va?žn??m ovliv??ovat progn??zu pacienta, p??sobit jeho morbiditu sni?žovat kvalitu ?života. Zat?­mco klasick?Š manifestace, jako jsou enteropatick?Š artropatie, ko?žn?­ či očn?­ posti?žen?­ nebo prim??rn?­ sklerozuj?­c?­ cholangitida, sd?­lej?­ s IBD společn?? imunopatologick?? mechanismus, cel?? ??ada dal???­ch chorobn??ch stav?? m???že vznikat podkladÄ? r??zn??ch anatomick??ch metabolick??ch abnormalit zp??soben??ch vlivem l?ŠÄby. Tato p??ehledov?? pr??ce zamÄ???uje nejčastÄ?j???­ mimost??evn?­ komplikace, an?Šmie, metabolick?? kostn?­ nemoc bili??rn?­ nefroliti??za, kter??mi setk??v??me v bÄ??žn?Š klinick?Š praxi.

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ژورنال

عنوان ژورنال: Vnitr?ni? le?kar?stvi?

سال: 2021

ISSN: ['0042-773X', '1801-7592']

DOI: https://doi.org/10.36290/vnl.2021.020