Extrahepatic cholestasis increases liver stiffness (FibroScan) irrespective of fibrosis

increased liver stiffness in extrahepatic cholestasis caused by choledocholithiasis

Increased liver stiffness in extrahepatic cholestasis caused by choledocholithiasis

BACKGROUND Extrahepatic cholestasis that is caused by benign and malignant diseases has been reported to increase liver stiffness (LS), as measured by transient elastography (TE). OBJECTIVES The aim of this study was to evaluate LS in patients with extrahepatic cholestasis due to choledocholithiasis before and after endoscopic sphincterotomy and stone removal. PATIENTS AND METHODS LS was me...

Fibroscan (transient elastography) for the measurement of liver fibrosis.

NHA The Fibroscan device (Echosens) works by measuring shear wave velocity. In this technique, a 50-MHz wave is passed into the liver from a small transducer on the end of an ultrasound probe (Figure 1). The probe also has a transducer on the end that can measure the velocity of the shear wave (in meters per second) as this wave passes through the liver. The shear wave velocity can then be conv...

Microsurgical Extrahepatic Cholestasis in the Rat: A Histopathological Liver Study

Fibrosis, bile duct proliferation and mast cell hyperplasia characterize extrahepatic cholestasis. We studied these liver alterations in a new microsurgical model of extrahepatic cholestasis in the rat. Male Wistar rats: Sham-operated (n=9) and Microsurgical Cholestasis (n=10). After 4 weeks, a liver morphometric study was carried out using an image analysis system to assess bile proliferation ...

Update of liver fibrosis and steatosis with transient elastography (Fibroscan)

BACKGROUND Assessment of liver fibrosis and steatosis is now almost indispensable in most of the chronic liver diseases in order to determine prognosis and need for treatment, and to monitor disease progression and response to treatment. Liver biopsy is limited by its invasiveness and patient acceptability. Transient elastography (TE; Fibroscan) is a non-invasive tool with satisfactory accuracy...