Extragonadal germ cell tumors.Clinicopathologic findings and treatment experience in 12 patients

Extragonadal germ cell tumors.

Germ cell cancer is the most common malignancy in men aged 15–35 years; 5% of the malignant germ cell tumors are of extragonadal origin [1]. An extragonadal germ cell tumor (EGGCT) is by definition a germ cell neoplasm displaying one of the histologies associated with gonadal origin, but located outside of the gonads. This specific clinical entity was first described in the 19th century [2, 3]....

extragonadal germ cell tumor and male infertility

background: over recent decades a possible decrease in sperm quality and an increase in the incidence of testicular cancer have been reported in many populations. some recent findings, as cohort studies, showed an increased risk of testicular cancer in men with abnormal semen analysis. case: a 30 years old man referred to our clinic with chief compliant of infertility for 3 years. spermogram re...

Is orchiectomy always necessary in retroperitoneal extragonadal germ cell tumours?

Case report: Extragonadal mixed germ cell tumor in the thigh

Germ cell tumors (GCTs) in males predominantly arise from testicular tissue, but 2e5% arise in extragonadal sites with no evidence of a primary testicular tumor, thus called extragonadal germ cell tumors (EGCTs). They mostly arise in the mid-axis of the body; 50e70% in the mediastinum, 30e40% in the retroperitoneal space, and fewer arise in the pineal gland and the suprasellar region. Few occur...

Protocol for the examination of specimens from pediatric and adult patients with extragonadal germ cell tumors.

Authors Amy Heerema-McKenney, MD* Department of Pathology, Stanford University, Palo Alto, California Jay Bowen, MS Center for Childhood Cancer, Columbus Children’s Research Institute, Columbus, Ohio D. Ashley Hill, MD Department of Pathology, Children’s National Medical Center, Washington, DC Stephen J. Qualman, MD** Center for Childhood Cancer, Columbus Children’s Research Institute, Columbus...