Extraesophageal Reflux and Upper Aerodigestive Tract Diseases
نویسندگان
چکیده
منابع مشابه
Extraesophageal reflux and upper aerodigestive tract diseases.
Reflux disease can cause multiple disorders not only of the esophagus but also of the upper aerodigestive tract. In the last decade, an association between reflux disease and multiple head and neck diseases was described, including those of the larynx and pharynx as well as those of the nose, the sinuses and the middle ear. The present article summarizes these different diseases and possible pa...
متن کاملExtraesophageal reflux in pediatric patients with upper respiratory symptoms.
OBJECTIVE To systematically review published literature describing the association between reflux and upper airway symptoms in children. DESIGN Structured MEDLINE search of English-language articles published since 1966. SUBJECTS We selected articles examining reflux in conjunction with stridor, apnea, sudden infant death syndrome, life-threatening events, and laryngomalacia. Studies that f...
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Chemoprevention is a clinical strategy to block or reverse carcinogenesis before the development of invasive cancer. Studies of chemoprevention in the lungs and upper aerodigestive tract have relied on the field carcinogenesis hypothesis, which predicts that diffuse epithelial injury will result from exposure of that epithelium to carcinogens. This hypothesis is supported by the frequent occurr...
متن کاملChemoprevention strategies for lung and upper aerodigestive tract cancer.
The field cancerization hypothesis suggests that carcinogen exposure affects the entire epithelial lining of the lungs and upper aerodigestive tract. The concept that common exposures place the entire epithelium at risk for the development of invasive cancer is supported both by the occurrence of premalignant lesions such as leukoplakia and squamous metaplasia, and by the development of multipl...
متن کاملCetuximab activity in dysplastic lesions of the upper aerodigestive tract.
BACKGROUND High risk head and neck mucosal premalignancy has a malignant conversion rate of up to 40%, despite adequate surgical therapy. Epidermal Growth Factor Receptor (EGFR) blocking agents, including cetuximab, have shown activity in head and neck squamous cell carcinoma (HNSCC) and have potential for therapy in high risk premalignancy. METHODS We conducted a randomized, prospective, pha...
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ژورنال
عنوان ژورنال: ORL
سال: 2005
ISSN: 0301-1569,1423-0275
DOI: 10.1159/000086662