Extracorporeal Shock Wave Treatment Improves Incisional Wound Healing in Diabetic Rats

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Improvement of Diabetic Wound Healing by ESWT

285 Received August 31, 2011; revision accepted for publication November 3, 2011. doi: 10.1620/tjem.225.285 Correspondence: Xiaoyu Yan, M.D., Ph.D., Department of Orthopedic Surgery, Shanghai Sixth People’s Hospital, Shanghai Jiao Tong University, No. 600, Yishan Road, Shanghai 200233, P.R. China. e-mail: yan [email protected] Extracorporeal Shock Wave Treatment Improves Incisional Wound Healing in...

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Extracorporeal shock wave therapy improves motor dysfunction and pain originating from knee osteoarthritis in rats.

OBJECTIVE Although there have been several reports on the use of extracorporeal shock wave therapy (ESWT), the efficacy of ESWT for knee osteoarthritis (OA) has not been clarified. The aim of this study is to investigate the effect of ESWT on OA in a rat knee model. METHODS The rats were divided into three groups: (1) control, (2) OA, and (3) ESWT (knee OA+shock wave therapy). Behavioral anal...

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Extracorporeal shock wave therapy in the treatment of a non-healing chronic venous leg ulcer

Extracorporeal shock waves are defined as a sequence of acoustic pulses characterised by a fast pressure rise to over 100 MPa, followed by a decrease to normal pressure within a few microseconds. In the 1980s, extracorporeal shock wave lithotripsy (ESWL) was first used for the treatment of urolithiasis. Orthopaedists then began to use extracorporeal shock wave therapy (ESWT) to treat non-union ...

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Antioxidant Sol-Gel Improves Cutaneous Wound Healing in Streptozotocin-Induced Diabetic Rats

We examined the effects of vitamin C in Pluronic F127 on diabetic wound healing. Full-thickness excision skin wounds were made in normal and diabetic Wistar rats to evaluate the effect of saline, saline plus vitamin C (antioxidant sol), Pluronic F127, or Pluronic F127 plus vitamin C (antioxidant sol-gel). The rate of wound contraction, the levels of epidermal and dermal maturation, collagen syn...

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Shock wave treatment enhances cell proliferation and improves wound healing by ATP release-coupled extracellular signal-regulated kinase (ERK) activation.

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying the beneficial effects of shock waves have not yet been fully revealed. Because cell proliferation is a major requirement in the wound healing cascade, we used in vitro studies and an in vivo wound healing model to study whether shock wave treatment influences proliferation...

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ژورنال

عنوان ژورنال: The Tohoku Journal of Experimental Medicine

سال: 2011

ISSN: 0040-8727,1349-3329

DOI: 10.1620/tjem.225.285