Extracellular volume fraction provides more imformation than fibrosis

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Extracellular volume fraction provides more imformation than fibrosis

Background Extracellular volume fraction (ECV) has been applied to the detection of diffuse myocardial interstitial fibrosis or exudative pathologic changes in various clinical settings, but there is lack of study to date concerning the significance of ECV at the early phase of left ventricular remodeling. We intended to assess myocardial ECV in essential hypertension and to study the implicati...

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Myocardial extracellular volume fraction and myocardial fibrosis by cmr in patients with severe aortic stenosis

Background Severe aortic stenosis (AS) induces diffuse interstitial myocardial fibrosis (MF). CMR late gadolinium enhancement (LGE) technique is useful to detect focal MF. The amount of MF is associated with worse long-term prognosis after aortic valve replacement surgery (AVR). Measurements of T1 relaxation times before and after gadolinium administration allow determination of myocardial extr...

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Extracellular volume fraction measured by MOLLI: slow infusion versus bolus

Background Myocardial extracellular volume fraction (Ve) measures from myocardial and blood pool T1 data quantify diffuse fibrosis (Flett, 2010) not detectable by conventional late gadolinium (Gd) enhancement, but require steady state equilibrium between plasma and interstitium. While a bolus with a lengthy infusion produces steady state for Ve measures, it is unclear whether a Gd contrast bolu...

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Automatic software for extracellular volume fraction mapping in the myocardium

Background CMR is a useful tool for myocardial tissue characterization and to assess fibrosis and edema non-invasively. The estimation of extracellular volume fraction (ECV) is emerging as accurate biomarkers in many cardiac diseases associated with diffuse myocardial fibrosis. In this work, we present our automatic tool for ECV map creation. All the computational system consists of an executab...

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ژورنال

عنوان ژورنال: Journal of Cardiovascular Magnetic Resonance

سال: 2015

ISSN: 1532-429X

DOI: 10.1186/1532-429x-17-s1-q134