منابع مشابه
Extracellular Microtubules
Mastigonemes (Flimmer) from the sperm of Ascophyllum and Fucus were found to consist of a tripartite structure-a ca. 2000-A tapered basal region, a closed microtubular shaft, and a group of terminal filaments. Each of these regions appears to be constructed of globular subunits with a center-to-center distance of about 45 A. The mastigoneme microtubule is of smaller diameter (170-190 A) than cy...
متن کاملTransferring information from microtubules to extracellular matrix
Commentary to: Li S, Lei L, Somerville CR, Gu Y. Cellulose synthase interactive protein 1 (CSI1) links microtubules and cellulose synthase complexes. Proc Natl Acad Sci U S A 2012; 109:185– 90; PMID:22190487; http://dx.doi.org/10.1073/ pnas.1118560109 and Bringmann M, Li E, Sampathkumar A, Kocabek T, Hauser MT, Persson S. POM-POM2/cellulose synthase interacting1 is essential for the functional ...
متن کاملExtracellular Microtubules in the Aphid Gut
As part of an investigation of a plant virus which multiplies within the cells of its aphid vector (O'Loughlin and Chambers, 1967), the fine structure of the aphid gut was studied. The alimentary canal of aphids commences with the food canal which is formed by the apposition of grooves in the two interlocking feeding stylets . The stylet food canal leads to the sucking or pharyngeal pump within...
متن کاملMISP: The missing link between extracellular matrix and astral microtubules
Positioning of the cell division plane is critically important for tissue morphogenesis and architecture. 1 it is therefore not surprising that mitotic spindle orientation must be tightly regulated in living tissues, a phenomenon that is also observed in cells cultured in vitro. Because of the amenability of cultured cells to molecular and physical manipulation, many investigators have used suc...
متن کاملMicrotubules regulate GEF-H1 in response to extracellular matrix stiffness
Breast epithelial cells sense the stiffness of the extracellular matrix through Rho-mediated contractility. In turn, matrix stiffness regulates RhoA activity. However, the upstream signaling mechanisms are poorly defined. Here we demonstrate that the Rho exchange factor GEF-H1 mediates RhoA activation in response to extracellular matrix stiffness. We demonstrate the novel finding that microtubu...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1969
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.40.2.446