Extracellular DNase activity of Cryptococcus neoformans and Cryptococcus gattii
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Extracellular DNase activity of Cryptococcus neoformans and Cryptococcus gattii.
Extracellular DNase activity was studied in 73 strains of Cryptococcus neoformans and 12 strains of Cryptococcus gattii. DNase activity was measured by DNase agar clearance with and without Methyl Green. All strains tested showed extracellular DNase activity and no significant difference was found betweenC. neoformans and C. gattii strains. DNase production was higher in strains from clinical o...
متن کاملBiological activity of Cryptococcus neoformans and Cryptococcus gattii from clinical and environmental isolates Atividade biológica de Cryptococcus neoformans e Cryptococcus gattii provenientes de isolados clínicos e ambientais
First submission on 23/05/12; last submission on 31/12/12; accepted for publication on 14/03/13; published on 20/06/13 1. Doctor im Microbiology by Universidade Federal de Minas Gerais (UFMG); assistant professor at Universidade Federal de Sergipe (UFSE). 2. Resident in Neurology at Universidade Federal de São Paulo (UNIFESP). 3. Resident in Cardiology at Instituto Dante Pazzanese. 4. Doctor in...
متن کاملCryptococcus neoformans and Cryptococcus gattii, the etiologic agents of cryptococcosis.
Cryptococcus neoformans and Cryptococcus gattii are the two etiologic agents of cryptococcosis. They belong to the phylum Basidiomycota and can be readily distinguished from other pathogenic yeasts such as Candida by the presence of a polysaccharide capsule, formation of melanin, and urease activity, which all function as virulence determinants. Infection proceeds via inhalation and subsequent ...
متن کاملDiversity of the Cryptococcus neoformans-Cryptococcus gattii species complex.
More than 110 years of study of the Cryptococcus neoformans and Cryptococcus gattii species complex has resulted in an enormous accumulation of fundamental and applied biological and clinical knowledge. Recent developments in our understanding of the diversity within the species complex are presented, emphasizing the intraspecific complexity, which includes species, microspecies, hybrids, serot...
متن کاملNovel Antifungal Activity for the Lectin Scytovirin: Inhibition of Cryptococcus neoformans and Cryptococcus gattii
Pathogenic cryptococci are encapsulated yeast that can cause severe meningoencephalitis. Existing therapeutic options are dated and there is a growing need for new alternative antifungal agents for these fungi. Here we report novel inhibition of pathogenic cryptococci by the antimicrobial lectin Scytovirin. Inhibition was most potent against Cryptococcus neoformans var neoformans and C. gattii,...
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ژورنال
عنوان ژورنال: Revista Iberoamericana de Micología
سال: 2010
ISSN: 1130-1406
DOI: 10.1016/j.riam.2009.11.004