External lung cancer risk factors in non-smokers

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Lung cancer in 'Never-smokers': molecular factors trump risk factors.

While they represent a minority of patients with lung cancer, more than 20,000 people in the United States who never smoked cigarettes are diagnosed with lung cancer each year.[1] This makes lung cancer in “never-smokers” one of the 10 most common cancers—more common than ovarian cancer. In this issue of ONCOLOGY, Subramanian and Govindan give an overview of emerging data about lung cancer in n...

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Pulmonary Cancer among Non Smokers - Risk Factors

Lung cancer remains the largest cause of cancer deaths worldwide and the overall 5-yr survival rate is only 15%. Approximately 85%–90% of all lung cancer deaths in the United States are caused by active cigarette smoking. The complex plurifactorial determinism of lung cancer, the intertwining and mutual conditioning of the risk factors, acting either directly (carcinogenic) or indirectly as fav...

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Lung cancer in non-smokers

The decrease in lung cancer mortality in many Western societies is being attributed to a large extent to smoking prevention measures. However, lung cancer also occurs in nonsmokers, with an estimated frequency of 10–25%. The identification of oncogenic driver alterations which are successfully targetable, being more prevalent in lung cancer in non-smokers, has encouraged interest in these tumor...

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Variations in lung cancer risk among smokers.

BACKGROUND Although there is no proven benefit associated with screening for lung cancer, screening programs are attracting many individuals who perceive themselves to be at high risk due to smoking. We sought to determine whether the risk of lung cancer varies predictably among smokers. METHODS We used data on 18 172 subjects enrolled in the Carotene and Retinol Efficacy Trial (CARET)-a larg...

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Lung cancer in never smokers: clinical epidemiology and environmental risk factors.

More than 161,000 lung cancer deaths are projected to occur in the United States in 2008. Of these, an estimated 10 to 15% will be caused by factors other than active smoking, corresponding to 16,000 to 24,000 deaths annually. Thus lung cancer in never smokers would rank among the most common causes of cancer mortality in the United States if considered as a separate category. Slightly more tha...

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ژورنال

عنوان ژورنال: Onkologie

سال: 2020

ISSN: 1802-4475,1803-5345

DOI: 10.36290/xon.2020.005