Extended- Versus Narrower-Spectrum Antibiotics for Appendicitis

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Extended- Versus Narrower-Spectrum Antibiotics for Appendicitis.

BACKGROUND AND OBJECTIVES Appendicitis guidelines recommend either narrower- or extended-spectrum antibiotics for treatment of complicated appendicitis. The goal of this study was to compare the effectiveness of extended-spectrum versus narrower-spectrum antibiotics for children with appendicitis. METHODS We performed a retrospective cohort study of children aged 3 to 18 years discharged betw...

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Antibiotics vs appendectomy for uncomplicated acute appendicitis.

The term evidence-based medicine was first coined by Sackprognosis of disease, how to quantify disease (measureett and colleagues as “the conscientious, explicit and judicious use of current best evidence in making decisions about the care of individual patients.” The key to practicing evidence-based medicine is applying the best current knowledge to decisions in individual patients. Medical kn...

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Meta‐analysis of antibiotics versus appendicectomy for non‐perforated acute appendicitis

BACKGROUND For more than a century, appendicectomy has been the treatment of choice for appendicitis. Recent trials have challenged this view. This study assessed the benefits and harms of antibiotic therapy compared with appendicectomy in patients with non-perforated appendicitis. METHODS A comprehensive search was conducted for randomized trials comparing antibiotic therapy with appendicect...

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Antibiotics versus appendectomy in the management of acute appendicitis: a review of the current evidence.

BACKGROUND Acute appendicitis remains the most common cause of the acute abdomen in young adults, and the mainstay of treatment in most centres is an appendectomy. However, treatment for other intra-abdominal inflammatory processes, such as diverticulitis, consists initially of conservative management with antibiotics. The aim of this study was to determine the role of antibiotics in the manage...

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Antibiotics versus appendicectomy in the management of acute appendicitis: an ongoing debate

Appendicitis remains the commonest cause of the acute abdomen in young adults and the mainstay of treatment at most centres remains an appendicectomy [1]. This is despite the fact that many other intra-abdominal pathologies, such as diverticulitis, are routinely managed conservatively with antibiotics. A study by Varadhan et al (2012) aimed to assess the safety and efficacy of antibiotic treatm...

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ژورنال

عنوان ژورنال: Pediatrics

سال: 2016

ISSN: 0031-4005,1098-4275

DOI: 10.1542/peds.2015-4547