Extended polysialic acid chains (n greater than 55) in glycoproteins from human neuroblastoma cells.

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Extended Polysialic Acid Chains ( n > 55 ) in Glycoproteins from Human Neuroblastoma Cells

Polysialic acid-containing glycoproteins consisting of extended chains of at least 55 sialyl residues (DP55, where DP represents degree of polymerization) are expressed on human neuroblastoma cells, CHP134. The strategy used for detecting these unique carbohydrate structures was based on the use of two highly specific prokaryotic-derived enzyme systems and an anti-polysialosyl antibody (H.46). ...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1988

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(19)76560-0