Extended Letrozole Regimen for Treatment of Clomiphene Resistant Polycystic Ovary Syndrome Patients
نویسندگان
چکیده
منابع مشابه
Letrozole versus clomiphene for infertility in the polycystic ovary syndrome.
BACKGROUND Clomiphene is the current first-line infertility treatment in women with the polycystic ovary syndrome, but aromatase inhibitors, including letrozole, might result in better pregnancy outcomes. METHODS In this double-blind, multicenter trial, we randomly assigned 750 women, in a 1:1 ratio, to receive letrozole or clomiphene for up to five treatment cycles, with visits to determine ...
متن کاملDosage Optimization for Letrozole Treatment in Clomiphene-Resistant Patients with Polycystic Ovary Syndrome: A Prospective Interventional Study
Objective. Dose adjustment for induction of ovulation is one of the most important problem. Methods. In a prospective interventional study, 44 clomiphene-resistant infertile patients (113 cycles) were selected from the Abolfazl Infertility Clinic of Bushehr University of Medical Sciences. Letrozole was given orally in a dose of 2.5 mg, 5 mg, and 7.5 mg, respectively. If the patient displayed no...
متن کاملNaltrexone treatment in clomiphene resistant women with polycystic ovary syndrome.
BACKGROUND Endogenous opiates may affect various aspects of reproductive and metabolic function in patients with polycystic ovary syndrome (PCOS). This study evaluated long-term inhibition of the opioid system using naltrexone in clomiphene citrate (CC)-resistant women with PCOS. METHODS A group of 30 infertile females with PCOS were evaluated; all subjects were obese, hyperandrogenic and hyp...
متن کاملCombined letrozole and clomiphene versus letrozole and clomiphene alone in infertile patients with polycystic ovary syndrome [Erratum]
[This corrects the article on p. 1427 in vol. 7.][This corrects the article on p. 1427 in vol. 7.].
متن کاملP-62: Extended Letrozole Therapy for Ovulation Induction in Women with Polycystic Ovary Syndrome
Background: Polycystic ovary syndrome (PCOS) is a common endocrine disorder in young women which has different clinical consequences. This study was conducted to evaluate the outcome of long or extended letrozole therapy for induction of ovulation in patients with polycystic ovary syndrome (PCOS). Materials and Methods: This prospective controlled study was conducted in a university hospital on...
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ژورنال
عنوان ژورنال: Benha Medical Journal
سال: 2021
ISSN: ['2357-0016', '1110-208X']
DOI: https://doi.org/10.21608/bmfj.2021.18571.1126