Expression of Vascular Endothelial Growth Factor in N-butyl-N-(4–hydroxybutyl)nitrosamine-induced Rat Bladder Carcinogenesis
نویسندگان
چکیده
منابع مشابه
Effects of promoters on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis in the rat.
It has been shown that the occurrence of the preneoplastic lesion, papillary or nodular hyperplasia (PN hyperplasia) in rat urinary bladder induced by carcinogens is correlated with that of cancer. Therefore, the promoting effects of chemicals in two-stage bladder carcinogenesis were judged by measuring their ability to induce PN hyperplasia in rats. Male rats were given N-butyl-N-(4-hydroxybut...
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Anatomical and functional vascular changes during rat urinary bladder carcinogenesis were studied by scanning electron microscopy of vascular casts, transmission electron microscopy of bladder capillaries, and fractional distributions of 51Cr-erythrocytes, 125I-human serum albumin, and 86RbCl which were used to determine vascular volume, permeability, and perfusion. Histopathological changes an...
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ژورنال
عنوان ژورنال: Veterinary Pathology
سال: 1999
ISSN: 0300-9858,1544-2217
DOI: 10.1354/vp.36-2-111