Expression of serotonin receptors in human lower esophageal sphincter
نویسندگان
چکیده
منابع مشابه
Expression of serotonin receptors in human lower esophageal sphincter
Serotonin (5-HT) is a neurotransmitter and vasoactive amine that is involved in the regulation of a large number of physiological functions. The wide variety of 5-HT-mediated functions is due to the existence of different classes of serotonergic receptors in the mammalian gastrointestinal tract and nervous system. The aim of this study was to explore the expression of multiple types of 5-HT rec...
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Lysophosphatidic acid (LPA) is a bioactive lipid that is involved in a variety of physiological and pathological processes occurring in the gastrointestinal tract. It acts via six distinct types of receptors, LPA1, LPA2, LPA3, LPA4, LPA5 and LPA6, which belong to the family of G protein-coupled receptors. The aim of the present study was to detect the expression of the LPA receptors in the huma...
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Serotonin (5-hydroxytryptamine, 5-HT) can stimulate the lower esophageal sphincter (LES) by indirect actions on the modulation of reflexes and by a direct action on smooth muscles. Aim:of this study was to investigate the role of 5-HT and selective 5-HT receptor subtypes in the regulation of the lower esophageal sphincter (LES) in the rat by measuring electromotor activity of the LES. Methods:T...
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ژورنال
عنوان ژورنال: Experimental and Therapeutic Medicine
سال: 2014
ISSN: 1792-0981,1792-1015
DOI: 10.3892/etm.2014.2050