Expression and clinical significance of extracellular matrix metalloproteinase inducer, EMMPRIN/CD147, in human osteosarcoma
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چکیده
منابع مشابه
CD147 (Extracellular Matrix Metalloproteinase Inducer-EMMPRIN) Expression by Human Articular Chondrocytes
Background: Integrins are a family of transmembrane proteins that allow communication between the extracellular matrix and the interior of cells. Chondrocytes, cells of articular cartilage, express integrins and these molecules appear to have a variety of roles including mechanotransduction. Integrins are known to associate with a number of accessory molecules such as CD147 that may act to regu...
متن کاملcd147 (extracellular matrix metalloproteinase inducer-emmprin) expression by human articular chondrocytes
background: integrins are a family of transmembrane proteins that allow communication between the extracellular matrix and the interior of cells. chondrocytes, cells of articular cartilage, express integrins and these molecules appear to have a variety of roles including mechanotransduction. integrins are known to associate with a number of accessory molecules such as cd147 that may act to regu...
متن کاملClinical significance of leukotriene b4 and extracellular matrix metalloproteinase inducer in acute coronary syndrome.
PURPOSE Leukotriene B4 (LTB4) and extracellular matrix metalloproteinase (EMMPRIN) have been suggested as modulators of atherosclerotic plaque instability. This study sought to evaluate the potential diagnostic implication of LTB4 and EMMPRIN in patients with acute coronary syndrome (ACS). METHODS Patients (n=153) who underwent coronary angiography, including 105 patients diagnosed with ACS, ...
متن کاملRegulation of extracellular matrix metalloproteinase inducer and matrix metalloproteinase expression by amphiregulin in transformed human breast epithelial cells.
Amphiregulin (AR) and epidermal growth factor effects on expression and activity of the extracellular matrix metalloproteinase inducer (EMMPRIN) were examined in NS2T2A1 breast tumor cells. Both growth factors induced mRNA and protein expression of EMMPRIN, and matrix metalloproteinase (MMP) -2 and -9 enzymatic activity. The induction of EMMPRIN by AR was mediated by epidermal growth factor rec...
متن کاملTransformed Human Breast Epithelial Cells in and Matrix Metalloproteinase Expression by Amphiregulin Regulation of Extracellular Matrix Metalloproteinase Inducer
Amphiregulin (AR) and epidermal growth factor effects on expression and activity of the extracellular matrix metalloproteinase inducer (EMMPRIN) were examined in NS2T2A1 breast tumor cells. Both growth factors induced mRNA and protein expression of EMMPRIN, and matrix metalloproteinase (MMP) -2 and -9 enzymatic activity. The induction of EMMPRIN by AR was mediated by epidermal growth factor rec...
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ژورنال
عنوان ژورنال: Oncology Letters
سال: 2012
ISSN: 1792-1074,1792-1082
DOI: 10.3892/ol.2012.981