Expression and characterization of recombinant interferon gamma (IFN-γ) from the nine-banded armadillo (Dasypus novemcinctus) and its effect on Mycobacterium leprae-infected macrophages
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Mycobacterium leprae in six-banded (Euphractus sexcinctus) and nine-banded armadillos (Dasypus novemcinctus) in Northeast Brazil.
Human beings are the main reservoir of the causative agent of leprosy, Mycobacterium leprae. In the Americas, nine-banded armadillos (Dasypus novemcinctus) also act as a reservoir for the bacillus. In the state of Ceará (CE), which is located in Northeast Brazil and is an endemic area of leprosy, there are several species of armadillos, including D. novemcinctus and Euphractus sexcinctus (six-b...
متن کاملPatterns of Mycobacterium Leprae Infection in Wild Nine-banded Armadillos (dasypus Novemcinctus) in Mississippi, Usa.
The nine-banded armadillo ( Dasypus novemcinctus ) is the only known nonhuman reservoir of Mycobacterium leprae , the causative agent of Hansen's disease or leprosy. We conducted a 6-yr study on a wild population of armadillos in western Mississippi that was exposed to M. leprae to evaluate the importance of demographic and spatial risk factors on individual antibody status. We found that spati...
متن کاملDetection of Mycobacterium leprae DNA in nine-banded armadillos (Dasypus novemcinctus) from the Andean region of Colombia.
OBJECTIVE To use DNA detection methodologies to test for M. leprae in nine-banded armadillos inhabiting forested regions located around the cities and towns where leprosy patients have been identified. DESIGN Ear lobe biopsies of 22 nine-banded armadillos were studied during a 2 year period. The biopsies were processed for DNA extraction and amplification by nested polymerase chain reaction (...
متن کاملVertebral bending mechanics and xenarthrous morphology in the nine-banded armadillo (Dasypus novemcinctus).
The vertebral column has evolved to accommodate the broad range of locomotor pressures found across vertebrate lineages. Xenarthran (armadillos, sloths and anteaters) vertebral columns are characterized by xenarthrous articulations, novel intervertebral articulations located in the posterior trunk that are hypothesized to stiffen the vertebral column to facilitate digging. To determine the degr...
متن کاملQuantitative investigation of the annual pattern of follicular development in the nine-banded armadillo (Dasypus novemcinctus).
Mature, non-pregnant, female armadillos (Dasypus novemcinctus) were killed throughout the year (3-6/month, N = 54) and both ovaries were examined for follicular development. All normal and atretic follicles > 358 micrometers were counte. Total number of normal follicles remained constant from January to June but decreased by 50% in the remaining months except in October and November. Follicles ...
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ژورنال
عنوان ژورنال: Cytokine
سال: 2008
ISSN: 1043-4666
DOI: 10.1016/j.cyto.2008.04.014