Exposure to Endocrine Disrupting Chemicals and Risk of Breast Cancer

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Endocrine disrupting chemicals and cancer risk (testis and breast)

There has been much concern whether Endocrine Disrupting Chemicals (EDCs) play a role in the recent increase in the incidence of certain hormone sensitive cancer forms. There is at present, however, no proven causal link between exposure to EDCs and human cancer in any of the organs supposed to be at highest risk, i.e., the testis, breast, prostate, and endometrium. This may be due to a real ab...

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Exposure to Endocrine Disrupting Chemicals and Male Reproductive Health

Endocrine disrupting chemicals (EDCs) can interfere with normal hormonal balance and may exert adverse consequences on humans. The male reproductive system may be susceptible to the effects of such environmental toxicants. This review discusses the recent progress in scientific data mainly from epidemiology studies on the associations between EDCs and male reproductive health and our understand...

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Risk Evaluation of Endocrine-Disrupting Chemicals

We review here our studies on early exposure to low doses of the estrogenic endocrine-disrupting chemical bisphenol A (BPA) on behavior and metabolism in CD-1 mice. Mice were exposed in utero from gestation day (GD) 11 to delivery (prenatal exposure) or via maternal milk from birth to postnatal day 7 (postnatal exposure) to 10 mg/kg body weight/d of BPA or no BPA (controls). Bisphenol A exposur...

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Risk of hypospadias in relation to maternal occupational exposure to potential endocrine disrupting chemicals.

BACKGROUND Reported rises in the prevalence of hypospadias and other abnormalities of the male reproductive system may be a result of exposure to endocrine disrupting chemicals. AIMS To analyse the relation between risk of hypospadias and maternal occupation, particularly with regard to exposure to potential endocrine disrupting chemicals (EDCs). METHODS Data (1980-96) from the National Con...

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Endocrine disrupting chemicals

The idea that xenobiotic chemicals could inappropriately modlate the endocrine system thereby causing detrimental effects n wildlife and humans was first proposed 20 years ago at the atershed Wingspread Conference [1,2]. These endocrine disruptng chemicals (EDCs) have long been controversial, with a great eal of discussion raging in the scientific literature. Much of this ontroversy has centere...

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ژورنال

عنوان ژورنال: International Journal of Molecular Sciences

سال: 2020

ISSN: 1422-0067

DOI: 10.3390/ijms21239139