Exploring the pleiotropic effects of vitamin D in diabetes
نویسندگان
چکیده
منابع مشابه
The Pleiotropic Effect of Vitamin D
The novel roles of vitamin D were discovered and valued in this century. In addition to the maintenance of calcium and phosphorus balance, vitamin D regulates the function of the kidneys, heart, and immune system. Moreover, its anti-inflammatory, antiapoptotic, and antifibrotic roles have gained considerable attention. Vitamin D is also important for the maintenance of homeostasis by regulation...
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1,25-Dihydroxvitamin D3 [1,25(OH)2D3] is the hormonally active form of vitamin D. The genomic mechanism of 1,25(OH)2D3 action involves the direct binding of the 1,25(OH)2D3 activated vitamin D receptor/retinoic X receptor (VDR/RXR) heterodimeric complex to specific DNA sequences. Numerous VDR co-regulatory proteins have been identified, and genome-wide studies have shown that the actions of 1,2...
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Vitamin D suppresses cellular pathways of diabetes complication in liver
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ژورنال
عنوان ژورنال: Galle Medical Journal
سال: 2018
ISSN: 1391-7072
DOI: 10.4038/gmj.v23i1.7987