Exploring polyamines: Functions in embryo/fetal development
نویسندگان
چکیده
منابع مشابه
Functions of Polyamines in Mammals.
The content of spermidine and spermine in mammalian cells has important roles in protein and nucleic acid synthesis and structure, protection from oxidative damage, activity of ion channels, cell proliferation, differentiation, and apoptosis. Spermidine is essential for viability and acts as the precursor of hypusine, a post-translational addition to eIF5A allowing the translation of mRNAs enco...
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The immune system is remarkably responsive to a myriad of invading microorganisms and provides continuous surveillance against tissue damage and developing tumor cells. To achieve these diverse functions, multiple soluble and cellular components must react in an orchestrated cascade of events to control the specificity, magnitude and persistence of the immune response. Numerous catabolic and an...
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Polyamines (putrescine, spermidine and spermine) are ubiquitous polycationic metabolites in prokaryotic and eukaryotic cells. Their roles in the regulation of major functions in cell growth, cell differentiation and their intricate and exquisitely regulated biosynthetic pathways have attracted considerable attention during the last few decades. Authoritative reviews and books have dealt with th...
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Mitochondrial DNA (mtDNA) mutations cause a wide range of serious diseases with high transmission risk and maternal inheritance. Tissue heterogeneity of the heteroplasmy rate ("mutant load") accounts for the wide phenotypic spectrum observed in carriers. Owing to the absence of therapy, couples at risk to transmit such disorders commonly ask for prenatal (PND) or preimplantation diagnosis (PGD)...
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ژورنال
عنوان ژورنال: Animal Nutrition
سال: 2017
ISSN: 2405-6545
DOI: 10.1016/j.aninu.2016.12.002