Exploring alternative routes for oxygen administration
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چکیده
منابع مشابه
Exploring alternative routes for oxygen administration
BACKGROUND Hypoxemia may compromise cell metabolism and organ function. Supplemental oxygen (O2) at high concentrations may prove ineffective, and issues relating to hyperoxia, barotrauma, mechanical ventilation, and extracorporeal oxygenation are well documented. Old reports suggest the potential safety and efficacy of alternative routes for O2 administration, such as intravenous or intestinal...
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The subcutaneous insulin drug therapy, vial and syringe method is burdenful and time consuming. Another question to design an alternative way to deliver insulin by replaces injectable insulin to move comfortable dosage form. Consequently more acceptable at least effective insulin delivery has been developed over past years. This review examines some of many attempts made to developed alternativ...
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Global polio eradication is closer than ever. Replacement of the live attenuated oral poliovirus vaccine (OPV) by inactivated poliovirus vaccine (IPV) is recommended to achieve complete eradication. Limited global production capacity and relatively high IPV costs compared to OPV spur the need for improved polio vaccines. The target product profile of these vaccines includes not only dose sparin...
متن کاملPharmacokinetics of Alternative Administration Routes of Melatonin: A Systematic Review
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BACKGROUND Melatonin is traditionally administered orally but has a poor and variable bioavailability. This study aims to present an overview of studies investigating the pharmacokinetics of alternative administration routes of melatonin. METHODS A systematic literature search was performed and included experimental or clinical studies, investigating pharmacokinetics of alternative administra...
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ژورنال
عنوان ژورنال: Intensive Care Medicine Experimental
سال: 2016
ISSN: 2197-425X
DOI: 10.1186/s40635-016-0108-z