Experimental Production of Cold Agglutinins in Rabbits

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Experimental Production of Cold Agglutinins in Rabbits.

By NICoi S COSTEA, VINCENT YAKULLS AND PAUL HELLER H EMOLYTIC ANEMIA of the cold agglutinin ( CA ) variety is believed to represent an autoimmune disorder occasionally complicating the course of lymphoproliferative diseases.’2 Whereas animal models have been proposed for the investigation of various autoimmune phenomena,3 cold reacting erythrocyte autoantibodies have not yet been studied in exp...

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From the Department of Pathology, University of Michigan Medical Center, Ann Arbor, Michigan. Address reprint requests to: W. John Judd, FIBMS, MIBiol, Professor of Immunohematology, Department of Pathology, UH-2G332, University of Michigan Medical Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0054; e-mail: [email protected]. Received for publication November 2, 2005; accepted No...

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So far as we know, a spontaneous growth of chorionic tumor has not been reported in any kind of animals. Recently, Shintani et al.1 first described an experimental chorionic tumor produced by carcinogenic agents in rats. For the last three years we have dealt with experimental production of chorionic tumor, and very recently have succeeded in producing a chorionic tumor by means of destruction ...

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I am grateful to Major-General J. Huston, Q.H.S., F.R.C.S., Director of Surgery, for his advice and encouragement and to Captain G. Tate, R.A.M.C., and Mr. A. E. Pridham, for their help. REFERENCES FINNEY, J. M. J., & HANRAHAN, E. M. (1930). Ann. Surg., 92, 620. GOLlGHER, J. C., MOIR, P. J. & WRIGLEY, J. H. (1956). Lancet, 1, 220. McDoNALD, O. G., GILLESPIE, M. G. & LA BREE, R. H. (1953). A.M.A...

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ژورنال

عنوان ژورنال: Blood

سال: 1965

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v26.3.323.323