Experimental postoperative ileus: is Th2 immune response involved?
نویسندگان
چکیده
منابع مشابه
Alvimopan for postoperative ileus
Purpose. The efficacy, safety, pharmacology, pharmacokinetics, drug–drug interactions, and administration of alvimopan for postoperative ileus are reviewed. Summary. Alvimopan is a selective mopioid receptor antagonist with no central nervous system activity. When orally administered after partial smallor largebowel resection in patients with primary anastomosis, alvimopan shortened the return ...
متن کاملManagement of postoperative ileus.
Postoperative ileus, a temporary cessation in bowel motility, is a common and significant complication of major surgery. Consequences of postoperative ileus include increased patient discomfort, delayed time to adequate nutrition, prolonged length of stay, and increased cost to the patient and healthcare system. The traditional, multi-modal approach to the resolution of postoperative ileus incl...
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Inflammation contributes to the pathogenesis of chronic kidney disease (CKD). Molecules released by the inflamed injured tissue can activate toll-like receptors (TLRs), thereby modulating macrophage and CD4(+) T-cell activity. We propose that in renal fibrogenesis, M2 macrophages are recruited and activated in a T helper subset 2 cell (T(H)2)-prone inflammatory milieu in a MyD88-dependent manne...
متن کاملPostoperative Ileus: Pathophysiology and Treatment
Postoperative ileus (POI) is a temporary impairment of gastrointestinal (GI) motility occurring universally after major abdominal surgery (Holte & Kehlet, 2002). For the majority of affected surgical patients, POI is transient, lasting approximately 3 to 5 days (Hotokezaka, et al., 1997). The adverse effects of POI are composed of not only physiologic effects such as reduced bowel function, exa...
متن کاملPostoperative Ileus A SPECIAL ARTICLE
13 INTRODUCTION Postoperative ileus (POI) is a very common problem after many surgical procedures, may lead to significant patient morbidity, and is a common reason for gastroenterological consultation. POI may be generally defined as transient inhibition of normal GI motility in the postoperative setting, typically lasting 3-5 days after surgery. Clinical consequences of POI include worsened p...
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ژورنال
عنوان ژورنال: International Journal of Medical Sciences
سال: 2021
ISSN: 1449-1907
DOI: 10.7150/ijms.59354