Experience of using ursodeoxycholic acid to dissolve gallstones
نویسندگان
چکیده
منابع مشابه
Ursodeoxycholic acid dissolution of gallstones in cystic fibrosis.
The dissolution of cholesterol gall stones is documented in two adults with cystic fibrosis. Improved care of patients with cystic fibrosis has meant that most survive into adult life. Consequently extrathoracic complications are assuming greater importance, especially those of the hepatobiliary system. These include progressive biliary cirrhosis (25%) leading to portal hypertension and oesopha...
متن کاملEffect of Ursodeoxycholic Acid Alone and Ursodeoxycholic Acid Plus Domperidone on Radiolucent Gallstones and Gallbladder Contractility in Humans
Background/Aims. The aim of this study was to compare the effects of ursodeoxycholic acid (UDCA) alone and UDCA plus domperidone on dissolution of solitary or multiple gallstones. Methods. Fifty-three patients with cholesterol gallstones were randomized into three treatment groups: group I (n = 22) was given UDCA (15 mg/kg/day) alone and group II (n = 18) was treated with domperidone (30 mg/day...
متن کاملUrsodeoxycholic acid
Ursodeoxycholic acid is an epimer of chenodeoxycholic acid (DB06777). It is a mammalian bile acid found first in the bear and is apparently either a precursor or a product of chenodeoxycholate. Its administration changes the composition of bile and may dissolve gallstones. It is used as a cholagogue and choleretic. [PubChem] Indication: The drug reduces cholesterol absorption and is used to dis...
متن کاملHepatic apolipoprotein A-I gene expression in patients with cholesterol gallstones treated with ursodeoxycholic acid.
OBJECTIVE It has been suggested that apo A-I can inhibit cholesterol crystal nucleation in vitro, and ursodeoxycholic acid (UDCA) is a safe and effective treatment for selected patients with cholesterol gallstones the aim of this study was to investigate the effect of UDCA on the steady-state levels (SSL) of apo A-I mRNA in the liver, as well as serum apo A-I, in patients with cholesterol galls...
متن کاملNutritional approaches to prevention and treatment of gallstones.
Cholesterol gallstones are among the most common gastrointestinal disorders in Western societies. Individuals with gallstones may experience various gastrointestinal symptoms and are also at risk of developing acute or chronic cholecystitis. Cholecystectomy is the most frequently recommended conventional treatment for symptomatic gallstones. Bile acids (ursodeoxycholic acid or chenodeoxycholic ...
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ژورنال
عنوان ژورنال: Medical Council
سال: 2020
ISSN: 2658-5790,2079-701X
DOI: 10.21518/2079-701x-2019-21-160-165