Exosomes and Their Role in Cancer Progression

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Exosomes and Their Role in Viral Infections

Exosomes are excretory nano-vesicles that are formed by the cell’s endocytic system and shed from the surface of almost all types of cells. These tiny extracellular vesicles, once thought to be “garbage bags for cells,” carry a wide variety of molecules of cellular origin, including proteins, lipids, and RNAs, that are selectively incorporated during the formation of exosomes. Exosomes are now ...

متن کامل

Tumor-derived exosomes in colorectal cancer progression and their clinical applications

Colorectal cancer (CRC) ranks as the third leading cause of cancer mortality in both of men and women worldwide due to its metastatic properties and resistance to current treatment. Recent studies have shown that tumor-derived exosomes play emerging roles in the development of cancer. Exosomes are nano-sized extracellular vesicles (EVs) that contain lipids, proteins, DNAs, and RNA species (mRNA...

متن کامل

Role of mesenchymal stem cells in growth and progression of cancer and prospective potentials in cancer therapy

Introduction: Mesenchymal stem cells (MSCs) are present in most tissues of the body. These cells are involved in various biological processes, such as maintaining tissue homeostasis and wound healing. Recent studies have shown that tumor associated MSCs (TA-MSCs) are also present in tumor microenvironment (TME) of most solid tumors. MSCs have a strong tendency to migration toward tumor tissues....

متن کامل

Dendritic Cells and Their Role in Cancer Immunotherapy

Dendritic cells (DCs) are antigen presenting cells with unique capability to take up and process antigens in the peripheral blood and tissues. They subsequently migrate to draining lymph nodes where they present these antigens and stimulate naive T lympho-cytes. During their life cycle, DCs go through two maturation stages and are referred to as immature and mature cells, respectively. While im...

متن کامل

Role of Rho GTPases and their regulators in cancer progression.

Rho family of GTPases is an ubiquitiously expressed and evolutionarily conserved family of GTP binding proteins that regulate actin dynamics and intracellular signaling. Among the Rho family GTPases, three members RhoA, Rac1 and CDC42 have been well characterized. They each play pivotal roles in gene expression, cell proliferation, apoptosis and various cellular functions. They are driven by si...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Frontiers in Oncology

سال: 2021

ISSN: 2234-943X

DOI: 10.3389/fonc.2021.639159