Exosome-Mediated Metastasis: Communication from a Distance

Exosome-mediated Lung Metastasis Formation In Osteosarcoma Progression

Emerging role of exosome-mediated intercellular communication in vascular remodeling

Vascular remodeling refers to the alternations of function and structure in vasculature. A complex autocrine/paracrine set of cellular interaction is involved in vascular remodeling. Exosome, a newly identified natural nanocarrier and intercellular messenger, plays a pivotal role in regulating cell-to-cell communication. Exosome emerges as an important mediator in the process of vascular remode...

Exosome-Mediated Genetic Information Transfer, a Missing Piece of Osteoblast–Osteoclast Communication Puzzle

The skeletal system functions and maintains itself based on communication between cells of diverse origins, especially between osteoblasts (OBs) and osteoclasts (OCs), accounting for bone formation and resorption, respectively. Previously, protein-level information exchange has been the research focus, and this has been discussed in detail. The regulative effects of microRNAs (miRNAs) on OB and...

Exosome/microvesicle-mediated epigenetic reprogramming of cells.

Microvesicles (MVs) are released by different cell types and may remain in the extracellular space in proximity of the cell of origin or may enter the biological fluids. MVs released by tumor cells are detectable in patients with cancer and their number in the circulation correlates with poor prognosis. Recent studies demonstrated that MVs may act as mediator of cell-to-cell communication thus ...

Solitary skull metastasis from follicular thyroid carcinoma: a case report

Introduction: Follicular thyroid carcinoma (FTC) is the second most common malignant form of thyroid cancers. FTC is more common in women with a peak incidence in the fifth and sixth decades of life. Invasion into blood vessels may lead to distant metastasis to bone, lung, liver or elsewhere. FTC rarely manifests itself as a distant metastatic lesion, especially as solitary metastasis. Case r...