Exome sequencing of multiple-sclerosis patients and their unaffected first-degree relatives
نویسندگان
چکیده
منابع مشابه
Emotion processing and theory of mind in schizophrenia patients and their unaffected first-degree relatives.
Previous studies have suggested that social cognition is affected in individuals with schizophrenia. The purpose of this study was to explore to what extent social cognition deficits are shared by unaffected first-degree relatives, and the nature of the relationship between performance in different paradigms of social cognition. 20 Schizophrenia patients (7 females, 31+/-10 years), 20 healthy a...
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Background: Genomic instability is one of primary causes for malignant cell transformation. In this study induced genomic instability expressed as micronuclei in breast cancer (BC) patients with different stages of the disease compared with their unaffected first degree relatives (FDR) and normal unrelated controls was investigated. Materials and Methods: The background and net micronucleus fre...
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Evidence has suggested that risk for schizophrenia is likely to occur in non-psychotic first-degree relatives of patients with schizophrenia. On the other hand, schizotypal personality disorder is genetically related to schizophrenia. The aim of this study was to compare schizotypal traits (i.e., positive schizotypy, negative schizotypy, cognitive disorganization, and impulsive nonconformity) a...
متن کاملNeurocognitive Impairments in Unaffected First-degree Relatives of Schizophrenia
BACKGROUND Neurocognitive impairments of attention and executive functioning are trait abnormalities in schizophrenia, and these are considered to be endophenotypes. These deficits have been convincingly linked to prefrontal cortical functioning. In this study, we examined the cognitive performance in the domains of attention and executive functioning among first-degree relatives of Indian peop...
متن کاملPersonality traits in adults with attention-deficit hyperactivity disorder and their unaffected first-degree relatives
BACKGROUND Attention-deficit hyperactivity disorder (ADHD) shows clear, albeit heterogeneous, cognitive dysfunctions. However, personality traits are not well understood in adults with ADHD, and it is unclear whether they are predisposing factors or phenotypical facets of the condition. AIMS To assess whether personality traits of impulsivity, sensation seeking and sensitivity to punishment a...
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ژورنال
عنوان ژورنال: BMC Research Notes
سال: 2017
ISSN: 1756-0500
DOI: 10.1186/s13104-017-3072-0