Excitation-Contraction Coupling and Minor Triadic Proteins in Low-Frequency Fatigue
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چکیده
منابع مشابه
Calmodulin modulation of proteins involved in excitation-contraction coupling.
Muscle excitation-contraction coupling is, in large part, regulated by the activity of two proteins. These are the ryanodine receptor (RyR), which is an intracellular Ca2+ release channel and the dihydropyridine receptor (DHPR), which is a voltage gated L-type calcium channel. In skeletal muscle, the physical association between RyR1 and L-type Ca2+ channels is required for muscle excitation-co...
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Heart Failure After Myocardial Infarction : Altered Excitation-Contraction Coupling Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2001 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/hc3201.092285 2001;104:688-693 Circulation. http://circ.ahajournals.org/content/10...
متن کاملExcitation-Contraction Coupling
Previous studies have demonstrated that the ability of (.adrenergic receptor (.BAR) stimulation to increase cardiac contractility declines with aging. In the present study, the control mechanisms of excitation-contraction (EC) coupling, including calcium current (Ice), cytosolic Ca2" (Ca?') transient and contraction in response to BAR stimulation were investigated in ventricular myocytes isolat...
متن کاملCalmodulin and Excitation-Contraction Coupling.
Excitation-contraction coupling in cardiac and skeletal muscle involves the transverse-tubule voltage-dependent Ca(2+) channel and the sarcoplasmic reticulum Ca(2+) release channel. Both of these ion channels bind and are modulated by calmodulin in both its Ca(2+)-bound and Ca(2+)-free forms. Calmodulin is, therefore, potentially an important regulator of excitation-contraction coupling. Its pr...
متن کاملExcitation-Contraction Coupling and Digitalis
T HE PRIMARY task of heart muscle is to develop force and shorten at regular intervals. The action potential is the initial step in triggering contraction of the heart, and it may also be an important regulator of contraction strength. The process that links this membrane electrical event to the contraction is given the broad name of excitation-contraction coupling. The more we have increased o...
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ژورنال
عنوان ژورنال: Exercise and Sport Sciences Reviews
سال: 2010
ISSN: 0091-6331
DOI: 10.1097/jes.0b013e3181e3734d