Excimer laser for anterior cornea

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HSP47 expression in cornea after excimer laser photoablation.

PURPOSE The expression of heat shock protein 47 (HSP47) was observed histologically to investigate the spatial and chronological effects of excimer laser photoablation. HSP47 expression after radial keratotomy (RK) was also investigated and compared with the effects after excimer laser photoablation. METHOD Twenty-eight male rabbits were used. The rabbits were divided with two groups and trea...

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Analysis of glycosaminoglycans in rabbit cornea after excimer laser keratectomy.

BACKGROUND/AIMS The biochemical basis for the development of subepithelial opacity of the cornea after excimer laser keratectomy has yet to be fully defined. The aim of this study was to evaluate the alterations of glycosaminoglycans (GAGs) after excimer laser keratectomy. METHODS Rabbit corneas were harvested on days 5, 10, 20, and 30 after excimer laser photoablation. The amount of main dis...

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Acute ultrastructural changes of cornea after excimer laser ablation.

Corneal ultrastructural changes induced by an argon fluoride excimer laser using different parameters were investigated. Twenty-eight rabbit corneas were ablated at light doses per pulse and repetition rates ranging from 25-800 mJ/cm2 and 1-100 Hz, respectively, at four different total light doses (25-150 J/cm2). Transmission electron microscopy showed that corneal ablations done at subthreshol...

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Evaluation of the Efficacy of Excimer Laser Ablation of Cross-Linked Porcine Cornea

BACKGROUND Combination of riboflavin/UVA cross-linking (CXL) and excimer laser ablation is a promising therapy for treating corneal ectasia. The cornea is strengthened by cross-linking, while the irregular astigmatism is reduced by laser ablation. This study aims to compare the efficacy of excimer laser ablation on porcine corneas with and without cross-linking. METHODS AND FINDINGS The porci...

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Re-epithelialization in cornea organ culture after chemical burns and excimer laser treatment.

OBJECTIVE To describe the epithelial healing rates observed in freshly cultured rabbit corneas chemically burned with high-concentration hydrochloric acid (HCl) and sodium hydroxide (NaOH) and subsequently treated with phototherapeutic keratectomy (PTK). METHODS We obtained 126 fresh corneoscleral rims from cadaveric New Zealand white rabbits. Each cornea was exposed to 4-mm cellulose sponges...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 1991

ISSN: 0007-1161

DOI: 10.1136/bjo.75.5.257