Excess Dietary Salt Alters Angiotensinergic Regulation of Neurons in the Rostral Ventrolateral Medulla
نویسندگان
چکیده
منابع مشابه
Excess dietary salt alters angiotensinergic regulation of neurons in the rostral ventrolateral medulla.
Excess dietary salt intake contributes to or exacerbates some forms of hypertension by increasing sympathetic nerve activity (SNA) and arterial blood pressure (ABP) through angiotensin II (Ang II) type 1 receptor activation in the rostral ventrolateral medulla (RVLM). Despite this interaction among dietary salt, Ang II, and the RVLM, no studies have directly examined whether dietary salt by its...
متن کاملDietary salt intake alters cardiovascular responses evoked from the rostral ventrolateral medulla.
The present experiments examined whether in rats consuming diets with either high NaCl content (8%) or low Na+ content (0.01%) for 2 wk excitatory inputs to the rostral ventrolateral medulla (RVLM) would be altered. In chloralose-anesthetized rats, injection of glutamate into the RVLM elicited a pressor response that, compared with rats fed a control diet, was 50% larger in rats fed a diet cont...
متن کاملRapid Communication Increased Dietary Salt Sensitizes Vasomotor Neurons of the Rostral Ventrolateral Medulla
Increased dietary salt sensitizes vasomotor neurons of the rostral ventrolateral medulla. Print ISSN: 0194-911X. Online ISSN: 1524-4563 Copyright © 1993 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Hypertension doi: 10.1161/01.HYP.22.6.929 1993;22:929-933 Hypertension. http://hyper.ahajournals.org/...
متن کاملIncreased dietary salt sensitizes vasomotor neurons of the rostral ventrolateral medulla.
Excess dietary sodium is a major contributing factor to the incidence and severity of hypertension. However, the precise mechanism or mechanisms by which salt contributes to the severity of hypertension are unknown. The region of the rostral ventrolateral medulla (RVLM) is a principal brain stem locus critical for the regulation of arterial blood pressure by the sympathetic nervous system. The ...
متن کاملVentral lamina terminalis mediates enhanced cardiovascular responses of rostral ventrolateral medulla neurons during increased dietary salt.
Increased dietary salt enhances sympathoexcitatory and sympathoinhibitory responses evoked from the rostral ventrolateral medulla (RVLM). The purpose of the present study was to determine whether neurons of the forebrain lamina terminalis (LT) mediated these changes in the RVLM. Male Sprague-Dawley rats with and without LT lesions were fed normal chow and given access to water or 0.9% NaCl for ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Hypertension
سال: 2008
ISSN: 0194-911X,1524-4563
DOI: 10.1161/hypertensionaha.108.118935